The publication of pre-analysis plans is gaining further mainstream attention as the open science movement within academic research expands. Additionally, some funding agencies require pre-analysis plans as a condition of their grant awards. This paper proposes the existing targeted learning roadmap as a framework for the construction of pre-analysis plans. It also discusses current standards for content and hurdles that may arise in public health and health policy settings, including the complexities of “Big Data,” when writing pre-analysis plans for observational studies in practice.
November 24, 2015